Open Science · Waitlist open

The open chemistry database
for virtual screening.

Open-source Curated Datasets with Millions of 3D-minimized Molecules Structures for Download, ADMET predictions, Molecular Descriptors, Fingerprints, Drug-likeness Filters, Similarity Search and more!

↳ Get first access when v1 ships

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MIT-licensed coreFree for academic useNo credit card · just an email
Built for

Drug discovery workflows, end-to-end.

From early hit-finding to candidate selection, Alchemia replaces the brittle stack of CSVs, scraped tables, and one-off scripts.

Virtual Screening

Filter millions of compounds against your target profile in seconds.

Natural Product Mining

Unified access to ChEMBL, COCONUT, and regional NP collections.

AI-Ready Datasets

Standardized features, fingerprints, and ADMET labels ready for ML.

Drug Discovery

3D conformers, minimization metadata, and lead optimization precomputed.

Inside v1

Built on real, measured numbers.

10M+
Curated molecules
deduplicated by InChIKey
100+
ADMET properties
permeability · tox · met
10M+
3D Conformers
minimized · MMFF94s
5+
Fingerprint Types
ECFP4 · MACCS
How it works

Four stages, one provenance trail.

Every molecule carries its source, license, and standardization history. Nothing is silently transformed.

Step 01

Ingest

Pull from 14+ public chemical sources with provenance preserved end-to-end.

Step 02

Standardize

Salt strip, tautomer canonicalize, charge normalize, InChIKey reconcile.

Step 03

Enrich

Compute properties, fingerprints, ADMET predictions, and 3D conformers.

Step 04

Serve

Query, download, and cite — through API, CLI, or signed-link bulk releases.

Data sources

Federated. Provenanced. Cited.

We ingest from the public chemical commons and preserve every source license, version, and citation hash.

ChEMBL
v34
COCONUT
natural
NCI
open
BrNPDB
regional
Enamine
REAL
Molport
screen
+ 8 more sources tracked · view release manifest
Limited cohort · first 2,000 researchers

Be among the first to query Alchemia.

Early cohort members get extended API rate limits, a direct line to the team, and a voice in the v1 schema.

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